Search results for "carbon nanodots"

showing 10 items of 19 documents

Carbon Nanodots for On Demand Chemophotothermal Therapy Combination to Elicit Necroptosis: Overcoming Apoptosis Resistance in Breast Cancer Cell Lines

2020

Background: Engineered luminescent carbon nanodots (CDs) are appealing nanomaterials for cancer image-guided photothermal therapy combining near infrared (NIR)&ndash

0301 basic medicineCancer ResearchtheranosticsNecroptosisanticancer phototherapynecroptosisSettore BIO/11 - Biologia Molecolare02 engineering and technologylcsh:RC254-282Article03 medical and health sciencesRIPK1breast cancermedicineirinotecan;carbon nanodotsirinotecanChemistrygene expression analysesCancerPhotothermal therapy021001 nanoscience & nanotechnologymedicine.diseaselcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensIrinotecan030104 developmental biologyOncologySettore CHIM/09 - Farmaceutico Tecnologico ApplicativoApoptosisDrug deliveryCancer cellCancer research0210 nano-technologymedicine.drugCancers
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Enhancing carbon dots fluorescence via plasmonic resonance energy transfer

2022

Using plasmonic interactions to engineer optical properties at the nanoscale is an important challenge of current photonics. Here we establish a general strategy to enhance the orange emission of carbon dots by coupling them to gold nanoparticles through a polymeric spacer in solution. We exploit the overlap between the surface plasmon resonance of gold and the electronic transitions of carbon dots to achieve a fivefold increase of their fluorescence in the orange region, which is usually very weak. We demonstrate that this enhancement stems from an ultrafast resonance energy transfer from the coherent plasmonic state of the gold nanoantenna to the coupled carbon dot. Our study advances the…

Energy transferMechanics of MaterialsMechanical EngineeringSettore FIS/01 - Fisica SperimentaleGeneral Materials ScienceCarbon nanodotsPlasmonic nanoparticlesCondensed Matter PhysicsFluorescenceMaterials Research Bulletin
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Carbon Nanodots as Functional Excipient to Develop Highly Stable and Smart PLGA Nanoparticles Useful in Cancer Theranostics

2020

Theranostic systems have attracted considerable attention for their multifunctional approach to cancer. Among these, carbon nanodots (CDs) emerged as luminescent nanomaterials due to their exceptional chemical properties, synthetic ease, biocompatibility, and for their photothermal and fluorescent properties useful in cancer photothermal therapy. However, premature renal excretion due to the small size of these particles limits their biomedical application. To overcome these limitations, here, hybrid poly(lactic-co-glycolic acid) (PLGA-CDs) nanoparticles with suitable size distribution and stability have been developed. CDs were decisive in the preparation of polymeric nanoparticles, not on…

Fluorescence-lifetime imaging microscopyphotothermal therapyBiocompatibilitylcsh:RS1-441Pharmaceutical ScienceExcipientNanoparticleNanotechnology02 engineering and technology010402 general chemistry01 natural sciencesArticleNanomaterialslcsh:Pharmacy and materia medicahybrid nanoparticleschemistry.chemical_compoundcarbon nanodotmedicinecarbon nanodotsViability assaycancer theranosticChemistryhybrid nanoparticlePLGAimagingPhotothermal therapy021001 nanoscience & nanotechnology0104 chemical sciencesPLGASettore CHIM/09 - Farmaceutico Tecnologico Applicativocancer theranostics0210 nano-technologymedicine.drugPharmaceutics
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Highly Homogeneous Biotinylated Carbon Nanodots: Red-Emitting Nanoheaters as Theranostic Agents toward Precision Cancer Medicine

2019

Very recent red-emissive carbon nanodots (CDs) have shown potential as near-infrared converting tools to produce local heat useful in cancer theranostics. Besides, CDs seem very appealing for clinical applications combining hyperthermia, imaging, and drug delivery in a single platform capable of selectively targeting cancer cells. However, CDs still suffer from dramatic dot-to-dot variability issues such that a rational design of their structural, optical, and chemical characteristics for medical applications has been impossible so far. Herein, we report for the first time a simple and highly controllable layer-by-layer synthesis of biotin-decorated CDs with monodisperse size distribution, …

Fluorescence-lifetime imaging microscopyphotothermal therapyMaterials scienceCell SurvivalAntineoplastic AgentsNanotechnology02 engineering and technology010402 general chemistrytargeted cancer therapy01 natural sciencesDrug Delivery Systemsbiotincarbon nanodotCell Line TumorCarbon nanodotsHumansGeneral Materials SciencePrecision MedicineRational designimagingPhotothermal therapy021001 nanoscience & nanotechnologyCarbonNanostructures0104 chemical sciencesbiotin; carbon nanodots; imaging; photothermal therapy; targeted cancer therapy.Settore CHIM/09 - Farmaceutico Tecnologico ApplicativoBiotinylationDrug deliveryCancer cellMCF-7 CellsSurface modification0210 nano-technologyACS Applied Materials & Interfaces
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Shifting the Photoresponse of ZnO Nanowires into the Visible Spectral Range by Surface Functionalization with Tailor-Made Carbon Nanodots

2018

We report on the surface functionalization of ZnO nanowires (NWs) with specifically synthesized carbon nanodots (C-dots, CDs) that allows us to shift the photoresponse of the NWs far into the visib...

Materials scienceVisible spectral rangeZno nanowiresNanotechnology02 engineering and technology010402 general chemistry021001 nanoscience & nanotechnology01 natural sciences0104 chemical sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsGeneral EnergyCarbon nanodotsSurface modificationPhysical and Theoretical Chemistry0210 nano-technologyThe Journal of Physical Chemistry C
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β-C3N4 Nanocrystals: Carbon Dots with Extraordinary Morphological, Structural, and Optical Homogeneity

2018

Carbon nanodots are known for their appealing optical properties, especially their intense fluorescence tunable in the visible range. However, they are often affected by considerable issues of optical and structural heterogeneity, which limit their optical performance and limit the practical possibility of applying these nanoparticles in several fields. Here we developed a synthesis method capable of producing a unique variety of carbon nanodots displaying an extremely high visible absorption strength (ε > 3 × 106 M(dot)−1 cm−1) and a high fluorescence quantum yield (73%). The high homogeneity of these dots reflects in many domains: morphological (narrow size distribution), structural (q…

Materials sciencebusiness.industryGeneral Chemical EngineeringSettore FIS/01 - Fisica SperimentaleNanoparticleQuantum yield02 engineering and technologyGeneral Chemistry010402 general chemistry021001 nanoscience & nanotechnologyLaser01 natural sciencesFluorescenceMolecular electronic transition0104 chemical scienceslaw.inventionNanocrystallawOptical cavityHomogeneity (physics)Materials Chemistrycarbon nanodots fluorescent nanopraticlesOptoelectronics0210 nano-technologybusinessChemistry of Materials
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Photocycle of Excitons in Nitrogen-Rich Carbon Nanodots: Implications for Photocatalysis and Photovoltaics

2020

Nitrogen-rich carbon nanodots have emerged as promising nanomaterials for a wide range of applications where a highly emissive and photoactive material with low toxicity and cost-effectiveness is required. One of their hallmarks is indeed a bright, tunable fluorescence of excitonic nature. Disentangling the origin of their optical absorption and fluorescence properties and uncovering relaxation channels and interactions with solvents are some of the most debated issues in the field. Uncovering these aspects is essential for targeted applications, especially in the fields of photocatalysis but also photovoltaics and optoelectronics. Here, we present dedicated transient absorption measurement…

Materials sciencecarbon nanodots carbon nitride surface exciton core exciton photocycle ultrafast spectroscopy exciton emission530 Physicsbusiness.industryExcitonNanotechnologyNanomaterialschemistry.chemical_compoundchemistryPhotovoltaics540 ChemistryUltrafast laser spectroscopyPhotocatalysisGeneral Materials ScienceNanodotbusinessAbsorption (electromagnetic radiation)Carbon nitrideACS Applied Nano Materials
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Temperature-Dependence of Solvent-Induced Stokes Shift and Fluorescence Tunability in Carbon Nanodots

2019

We carried out a cryogenic investigation on the optical properties of carbon dots, aiming to better understand their emission mechanism and the role of the solvent. The solvatochromic Stokes shift is quantified by a low temperature approach which allows freezing of the photo-excited state of carbon dots, preventing any solvation relaxation. Moreover, the reduction in temperature helps to identify the dynamical inhomogeneous contribution to the broadening of the emission band; therefore, disentangling the role of solvent from other types of broadening, such as the homogeneous and the static inhomogeneous contributions.

Materials sciencefluorescence tunabilitychemistry.chemical_element02 engineering and technology010402 general chemistry01 natural scienceslcsh:QD241-441symbols.namesakelcsh:Organic chemistrycarbon nanodotCarbon nanodotsStokes shiftcarbon nanodotsSettore FIS/01 - Fisica SperimentaleRelaxation (NMR)SolvatochromismSolvationGeneral Medicine021001 nanoscience & nanotechnologycryogenic optical studyFluorescence0104 chemical sciencesSolventchemistryChemical physicssymbols0210 nano-technologyCarbonC
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Carbon Nanodots: A Review—From the Current Understanding of the Fundamental Photophysics to the Full Control of the Optical Response

2018

Carbon dots (CDs) are an emerging family of nanosystems displaying a range of fascinating properties. Broadly speaking, they can be described as small, surface-functionalized carbonaceous nanoparticles characterized by an intense and tunable fluorescence, a marked sensitivity to the environment and a range of interesting photochemical properties. CDs are currently the subject of very intense research, motivated by their possible applications in many fields, including bioimaging, solar energy harvesting, nanosensing, light-emitting devices and photocatalyis. This review covers the latest advancements in the field of CDs, with a focus on the fundamental understanding of their key photophysica…

PhotoluminescenceMaterials science530 PhysicsultrafastphotophysicNanoparticleNanotechnology02 engineering and technology010402 general chemistry01 natural sciencesElectronic stateslcsh:QD241-441lcsh:Organic chemistryCarbon nanodotscarbon dots540 Chemistryfemtosecondcarbon dotphotophysicsphotochemistrynanocarbonSettore FIS/01 - Fisica SperimentaleGeneral Medicine021001 nanoscience & nanotechnology0104 chemical sciencesSolar energy harvestingFemtosecondfluorescence0210 nano-technologyUltrashort pulse
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Effect of Halogen Ions on the Photocycle of Fluorescent Carbon Nanodots

2019

Carbon dots (C-dots) are well-known for their strong sensitivity to the environment, which reflects on intensity and shape changes of their fluorescence, induced by various interacting ions and molecules in solution. Although these interactions have been extensively studied in the last few years, especially in view of their possible sensing applications, the existing works have mostly focused on the quenching of C-dot fluorescence induced by metal cations. In fact, these latter easily bind to C-dots surfaces, which are negatively charged in most cases, promoting an electron transfer from the surface to them. Much less is known from the literature on the effect induced on C-dots by prototypi…

Photoluminescencequenchingfluorescence quenching02 engineering and technology010402 general chemistryPhotochemistryultrafast transient absorption01 natural sciencesIonlcsh:QD241-441lcsh:Organic chemistrycarbon nanodotheavy atom effectPhysics::Atomic and Molecular ClustersMoleculecarbon nanodotsQuenching (fluorescence)ChemistrySettore FIS/01 - Fisica SperimentaleGeneral Medicine021001 nanoscience & nanotechnologyFluorescence0104 chemical sciencesIntersystem crossingHalogenAbsorption (chemistry)0210 nano-technologyC
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